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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EFHA2
All Species:
22.73
Human Site:
Y398
Identified Species:
55.56
UniProt:
Q86XE3
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86XE3
NP_859074.1
530
60711
Y398
F
A
H
I
L
L
R
Y
T
N
V
E
N
T
S
Chimpanzee
Pan troglodytes
XP_519613
530
60695
Y398
F
A
H
I
L
L
R
Y
T
N
V
E
N
T
S
Rhesus Macaque
Macaca mulatta
XP_001094797
530
60679
Y398
F
A
H
I
L
L
R
Y
T
N
V
E
N
T
S
Dog
Lupus familis
XP_848512
537
61387
Y405
F
A
H
I
L
L
R
Y
T
N
V
E
N
T
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9CTY5
523
59792
Y391
F
A
H
I
L
L
R
Y
T
N
V
E
N
T
S
Rat
Rattus norvegicus
Q99P63
432
49423
G307
V
R
E
K
L
S
V
G
E
S
I
S
L
D
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420691
752
84225
Y620
F
A
H
I
L
L
R
Y
T
N
V
E
N
T
S
Frog
Xenopus laevis
NP_001090059
430
49121
G305
V
Q
A
R
I
P
P
G
E
S
I
S
M
D
E
Zebra Danio
Brachydanio rerio
A4IG32
489
55907
G348
G
M
L
L
A
Y
S
G
V
Q
S
R
K
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392106
461
54367
D336
Q
L
D
T
D
E
Y
D
K
Y
L
D
R
I
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
96
90.5
N.A.
91.5
37.9
N.A.
N.A.
55.9
39.2
20.5
N.A.
N.A.
41.1
N.A.
N.A.
Protein Similarity:
100
99.8
96.5
92.3
N.A.
93.5
53.7
N.A.
N.A.
62.3
55.6
38.6
N.A.
N.A.
56.2
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
6.6
N.A.
N.A.
100
0
0
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
20
N.A.
N.A.
100
20
6.6
N.A.
N.A.
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
60
10
0
10
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
10
0
0
10
0
0
0
10
0
20
0
% D
% Glu:
0
0
10
0
0
10
0
0
20
0
0
60
0
0
20
% E
% Phe:
60
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
0
0
0
30
0
0
0
0
0
0
0
% G
% His:
0
0
60
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
60
10
0
0
0
0
0
20
0
0
10
0
% I
% Lys:
0
0
0
10
0
0
0
0
10
0
0
0
10
0
10
% K
% Leu:
0
10
10
10
70
60
0
0
0
0
10
0
10
10
10
% L
% Met:
0
10
0
0
0
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
60
0
0
60
0
0
% N
% Pro:
0
0
0
0
0
10
10
0
0
0
0
0
0
0
0
% P
% Gln:
10
10
0
0
0
0
0
0
0
10
0
0
0
0
0
% Q
% Arg:
0
10
0
10
0
0
60
0
0
0
0
10
10
0
0
% R
% Ser:
0
0
0
0
0
10
10
0
0
20
10
20
0
0
60
% S
% Thr:
0
0
0
10
0
0
0
0
60
0
0
0
0
60
0
% T
% Val:
20
0
0
0
0
0
10
0
10
0
60
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
10
60
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _